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Zinc-dependent post-transcriptional control of hepatocyte fate in and regeneration of alcohol-associated liver disease
From the report
Zinc is an essential trace element that plays a fundamental role in cellular growth, differentiation and stress adaptation. At the molecular level, zinc is required for DNA synthesis, RNA transcription and cell-cycle progression, and it exerts broad regulatory effects on gene expression through its incorporation into metal-binding proteins. A particularly important class of zinc-dependent proteins…