Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysis

From the report

Nature Aging, Published online: 23 October 2026; doi:10.1038/s43587-026-01247-3The Human Aging Endothelial Cell Atlas reveals how gene expression patterns of the human endothelium change with age, identifying reduced angiogenesis, altered mechanical signaling and a conserved gene program linked to endothelial senescence.